Toluca (also Toluca de Lerdo) was a pre-columbian cultural center and is now the capital of Mexico State.
This is one of the most industrialized and prosperous cities in all of Mexico, a city of numerous factories, hospitals, universities, athletic events, and cultural venues. Toluca is due west of Mexico City, at almost 9,000 feet. After coming from Mexico City, you will be impressed with the clean air, but may get altitude sickness your first day there, so take it easy. Also, bring warm clothing. Nights are always cold, and there may be severe hail any time of year.
Toluca has its own international airport (IATA: TLC) serving many private jets, some U.S. airlines and several Mexican airlines (e.g., Interjet).
International airport in Mexico City is another alternative.